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Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism

Metabolic syndrome (MetS) is intricately linked to dysregulation of gut microbiota and host metabolomes. Here, we first find that a purified citrus polymethoxyflavone-rich extract (PMFE) potently ameliorates high-fat diet (HFD)–induced MetS, alleviates gut dysbiosis, and regulates branched-chain ami...

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Detalles Bibliográficos
Autores principales: Zeng, Su-Ling, Li, Shang-Zhen, Xiao, Ping-Ting, Cai, Yuan-Yuan, Chu, Chu, Chen, Bai-Zhong, Li, Ping, Li, Jing, Liu, E-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941918/
https://www.ncbi.nlm.nih.gov/pubmed/31922003
http://dx.doi.org/10.1126/sciadv.aax6208