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Conditional control of RNA-guided nucleic acid cleavage and gene editing

Prokaryotes use repetitive genomic elements termed CRISPR (clustered regularly interspaced short palindromic repeats) to destroy invading genetic molecules. Although CRISPR systems have been widely used in DNA and RNA technology, certain adverse effects do occur. For example, constitutively active C...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Ru, Wu, Ling-Yu, Huang, Hai-Yan, Xiong, Wei, Liu, Jian, Wei, Lai, Yin, Ping, Tian, Tian, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941951/
https://www.ncbi.nlm.nih.gov/pubmed/31900392
http://dx.doi.org/10.1038/s41467-019-13765-3