Accurate quantification of circular RNAs identifies extensive circular isoform switching events

Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and RNase R treatment efficiency, and underestimation of back-spliced junction reads. Here, we propose a novel algorithm, CIRIquant, for accurate c...

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Detalles Bibliográficos
Autores principales: Zhang, Jinyang, Chen, Shuai, Yang, Jingwen, Zhao, Fangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941955/
https://www.ncbi.nlm.nih.gov/pubmed/31900416
http://dx.doi.org/10.1038/s41467-019-13840-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941955/
https://www.ncbi.nlm.nih.gov/pubmed/31900416
http://dx.doi.org/10.1038/s41467-019-13840-9

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