Cargando…

Mapping axon initial segment structure and function by multiplexed proximity biotinylation

Axon initial segments (AISs) generate action potentials and regulate the polarized distribution of proteins, lipids, and organelles in neurons. While the mechanisms of AIS Na(+) and K(+) channel clustering are understood, the molecular mechanisms that stabilize the AIS and control neuronal polarity...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamdan, Hamdan, Lim, Brian C., Torii, Tomohiro, Joshi, Abhijeet, Konning, Matthias, Smith, Cameron, Palmer, Donna J., Ng, Philip, Leterrier, Christophe, Oses-Prieto, Juan A., Burlingame, Alma L., Rasband, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941957/
https://www.ncbi.nlm.nih.gov/pubmed/31900387
http://dx.doi.org/10.1038/s41467-019-13658-5