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Mapping axon initial segment structure and function by multiplexed proximity biotinylation
Axon initial segments (AISs) generate action potentials and regulate the polarized distribution of proteins, lipids, and organelles in neurons. While the mechanisms of AIS Na(+) and K(+) channel clustering are understood, the molecular mechanisms that stabilize the AIS and control neuronal polarity...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941957/ https://www.ncbi.nlm.nih.gov/pubmed/31900387 http://dx.doi.org/10.1038/s41467-019-13658-5 |