Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5(−)CD44(+) cells

Areas of a junction between two types of epithelia are known to be cancer-prone in many organ systems. However, mechanisms for preferential malignant transformation at the junction areas remain insufficiently elucidated. Here we report that inactivation of tumor suppressor genes Trp53 and Rb1 in the...

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Detalles Bibliográficos
Autores principales: Fu, Dah-Jiun, Wang, Lianghai, Chouairi, Fouad K., Rose, Ian M., Abetov, Danysh A., Miller, Andrew D., Yamulla, Robert J., Schimenti, John C., Flesken-Nikitin, Andrea, Nikitin, Alexander Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941991/
https://www.ncbi.nlm.nih.gov/pubmed/31901081
http://dx.doi.org/10.1038/s41467-019-13847-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941991/
https://www.ncbi.nlm.nih.gov/pubmed/31901081
http://dx.doi.org/10.1038/s41467-019-13847-2

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