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From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

The term “propagon” is used to define proteins that may transmit misfolding in vitro, in tissues or in organisms. Among propagons, misfolded tau is thought to be involved in the pathogenic mechanisms of various “tauopathies” that include Alzheimer's disease, progressive supranuclear palsy, and...

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Detalles Bibliográficos
Autores principales: Colin, Morvane, Dujardin, Simon, Schraen-Maschke, Susanna, Meno-Tetang, Guy, Duyckaerts, Charles, Courade, Jean-Philippe, Buée, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942016/
https://www.ncbi.nlm.nih.gov/pubmed/31686182
http://dx.doi.org/10.1007/s00401-019-02087-9