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White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy

Multiple system atrophy (MSA) is a fatal late-onset neurodegenerative disease. Although presenting with distinct pathological hallmarks, which in MSA consist of glial cytoplasmic inclusions (GCIs) containing fibrillar α-synuclein in oligodendrocytes, both MSA and Parkinson’s disease are α-synucleino...

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Detalles Bibliográficos
Autores principales: Bettencourt, Conceição, Foti, Sandrine C., Miki, Yasuo, Botia, Juan, Chatterjee, Aparajita, Warner, Thomas T., Revesz, Tamas, Lashley, Tammaryn, Balazs, Robert, Viré, Emmanuelle, Holton, Janice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942018/
https://www.ncbi.nlm.nih.gov/pubmed/31535203
http://dx.doi.org/10.1007/s00401-019-02074-0