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Human NORs, comprising rDNA arrays and functionally conserved distal elements, are located within dynamic chromosomal regions

Human nucleolar organizer regions (NORs), containing ribosomal gene (rDNA) arrays, are located on the p-arms of acrocentric chromosomes (HSA13–15, 21, and 22). Absence of these p-arms from genome references has hampered research on nucleolar formation. Previously, we assembled a distal junction (DJ)...

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Detalles Bibliográficos
Autores principales: van Sluis, Marjolein, Gailín, Michael Ó, McCarter, Joseph G.W., Mangan, Hazel, Grob, Alice, McStay, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942050/
https://www.ncbi.nlm.nih.gov/pubmed/31727772
http://dx.doi.org/10.1101/gad.331892.119