Cargando…

TRIM3 Negatively Regulates Autophagy Through Promoting Degradation of Beclin1 in Ewing Sarcoma Cells

BACKGROUND AND AIM: Ewing sarcoma (ES) is an aggressive neoplasm predominantly occurring in adolescents and has a poor prognosis when metastasized. In the current study, we were aiming to investigate the function of TRIM3 in autophagy in ES cells. METHODS: The expression of TRIM3 in Ewing sarcoma ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Qunshan, Zhang, Yuankai, Ma, Liang, Li, Deqiang, Li, Ming, Liu, Peilai, Li, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942252/
https://www.ncbi.nlm.nih.gov/pubmed/32021240
http://dx.doi.org/10.2147/OTT.S219777