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LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway

BACKGROUND: LncRNA LINC00662 is closely related to the occurrence and development of cancer. This study aims to explore the effect of LINC00662 on colon cancer tumor growth and metastasis and its molecular mechanism. METHODS: CCK8, colony formation, transwell, scratch wound, TUNEL, flow cytometry, R...

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Detalles Bibliográficos
Autores principales: Cheng, Bo, Rong, Aimei, Zhou, Quanbo, Li, Wenlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942292/
https://www.ncbi.nlm.nih.gov/pubmed/31900207
http://dx.doi.org/10.1186/s13046-019-1510-7