Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial

ABSTRACT: The MIRACLE trial (MERS-CoV Infection tReated with A Combination of Lopinavir/ritonavir and intErferon-β1b) investigates the efficacy of a combination therapy of lopinavir/ritonavir and recombinant interferon-β1b provided with standard supportive care, compared to placebo provided with sta...

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Detalles Bibliográficos
Autores principales: Arabi, Yaseen M., Asiri, Ayed Y., Assiri, Abdullah M., Aziz Jokhdar, Hani A., Alothman, Adel, Balkhy, Hanan H., AlJohani, Sameera, Al Harbi, Shmeylan, Kojan, Suleiman, Al Jeraisy, Majed, Deeb, Ahmad M., Memish, Ziad A., Ghazal, Sameeh, Al Faraj, Sarah, Al-Hameed, Fahad, AlSaedi, Asim, Mandourah, Yasser, Al Mekhlafi, Ghaleb A., Sherbeeni, Nisreen Murad, Elzein, Fatehi Elnour, Almotairi, Abdullah, Al Bshabshe, Ali, Kharaba, Ayman, Jose, Jesna, Al Harthy, Abdulrahman, Al Sulaiman, Mohammed, Mady, Ahmed, Fowler, Robert A., Hayden, Frederick G., Al-Dawood, Abdulaziz, Abdelzaher, Mohamed, Bajhmom, Wail, Hussein, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942374/
https://www.ncbi.nlm.nih.gov/pubmed/31900204
http://dx.doi.org/10.1186/s13063-019-3846-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942374/
https://www.ncbi.nlm.nih.gov/pubmed/31900204
http://dx.doi.org/10.1186/s13063-019-3846-x

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