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Genome-wide analysis of aberrant methylation of enhancer DNA in human osteoarthritis

BACKGROUND: Osteoarthritis is a chronic musculoskeletal disease characterized by age-related gradual thinning and a high risk in females. Recent studies have shown that DNA methylation plays important roles in osteoarthritis. However, the genome-wide pattern of methylation in enhancers in osteoarthr...

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Detalles Bibliográficos
Autores principales: Lin, Xiaozong, Li, Li, Liu, Xiaojuan, Tian, Jun, Zheng, Weizhuo, Li, Jin, Wang, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942377/
https://www.ncbi.nlm.nih.gov/pubmed/31900157
http://dx.doi.org/10.1186/s12920-019-0646-9