Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells

BACKGROUND: Adult human pancreatic beta cells are the “gold standard” for studies on diabetes pathogenesis, but their use is limited by insufficient availability and variable quality. An important effort has recently taken place to differentiate beta cells from human induced pluripotent stem cells (...

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Detalles Bibliográficos
Autores principales: Demine, Stéphane, Schiavo, Andrea Alex, Marín-Cañas, Sandra, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942385/
https://www.ncbi.nlm.nih.gov/pubmed/31900242
http://dx.doi.org/10.1186/s13287-019-1523-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942385/
https://www.ncbi.nlm.nih.gov/pubmed/31900242
http://dx.doi.org/10.1186/s13287-019-1523-3

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