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Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products

BACKGROUND: The recent concept of secretome-based tissue regeneration has profoundly altered the field of regenerative medicine and offers promising novel therapeutic options. In contrast to medicinal products with a single active substance, cell-derived secretomes comprise pleiotropic bioactive ing...

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Detalles Bibliográficos
Autores principales: Laggner, Maria, Gugerell, Alfred, Bachmann, Christiane, Hofbauer, Helmut, Vorstandlechner, Vera, Seibold, Marcus, Gouya Lechner, Ghazaleh, Peterbauer, Anja, Madlener, Sibylle, Demyanets, Svitlana, Sorgenfrey, Dirk, Ostler, Tobias, Erb, Michael, Mildner, Michael, Ankersmit, Hendrik Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942406/
https://www.ncbi.nlm.nih.gov/pubmed/31900195
http://dx.doi.org/10.1186/s13287-019-1524-2