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Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products
BACKGROUND: The recent concept of secretome-based tissue regeneration has profoundly altered the field of regenerative medicine and offers promising novel therapeutic options. In contrast to medicinal products with a single active substance, cell-derived secretomes comprise pleiotropic bioactive ing...
Autores principales: | Laggner, Maria, Gugerell, Alfred, Bachmann, Christiane, Hofbauer, Helmut, Vorstandlechner, Vera, Seibold, Marcus, Gouya Lechner, Ghazaleh, Peterbauer, Anja, Madlener, Sibylle, Demyanets, Svitlana, Sorgenfrey, Dirk, Ostler, Tobias, Erb, Michael, Mildner, Michael, Ankersmit, Hendrik Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942406/ https://www.ncbi.nlm.nih.gov/pubmed/31900195 http://dx.doi.org/10.1186/s13287-019-1524-2 |
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