Cargando…

Ubiquitin carboxyl‐terminal hydrolase L1 promotes hypoxia‐inducible factor 1‐dependent tumor cell malignancy in spheroid models

Hypoxia‐inducible factor 1 (HIF‐1) is a critical heterodimeric transcription factor for tumor malignancy. Recently, ubiquitin carboxyl‐terminal hydrolase L1 (UCHL1) has been reported to function as a deubiquitinating enzyme for the stabilization of its α subunit (HIF‐1α). In the present study, we sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xuebing, Hattori, Akira, Takahashi, Senye, Goto, Yoko, Harada, Hiroshi, Kakeya, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942421/ https://www.ncbi.nlm.nih.gov/pubmed/31729096 http://dx.doi.org/10.1111/cas.14236

Ejemplares similares

Overexpression of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in boys with cryptorchidism
por: Toliczenko-Bernatowicz, Dorota, et al.
Publicado: (2018)

Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma
por: Seliger, Barbara, et al.
Publicado: (2009)

Pivotal Role of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) in Uterine Leiomyoma
por: Suzuki, Tomoo, et al.
Publicado: (2023)

Ubiquitin Carboxyl-Terminal Hydrolases (UCHs): Potential Mediators for Cancer and Neurodegeneration
por: Sharma, Amit, et al.
Publicado: (2020)

Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo
por: Zhang, Mingming, et al.
Publicado: (2014)

Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease
por: Öhrfelt, Annika, et al.
Publicado: (2016)

Ubiquitin Carboxyl-Terminal Hydrolases and Human Malignancies: The Novel Prognostic and Therapeutic Implications for Head and Neck Cancer
por: Rong, Chao, et al.
Publicado: (2021)

The expression and clinical value of ubiquitin carboxyl-terminal hydrolase L1 in the blood of neonates with hypoxic ischemic encephalopathy
por: Zeng, Shuying, et al.
Publicado: (2021)

Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis
por: Hurst-Kennedy, Jennifer, et al.
Publicado: (2012)

Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis
por: Hayama, Ryosuke, et al.
Publicado: (2019)

Changes and significance of serum ubiquitin carboxyl-terminal hydrolase L1 and glial fibrillary acidic protein in patients with glioma
por: Zhu, Qing-Hua, et al.
Publicado: (2023)

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation
por: Ummanni, Ramesh, et al.
Publicado: (2011)

Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression
por: Kwan, Suet-Ying, et al.
Publicado: (2020)

High-level expression of active recombinant ubiquitin carboxyl-terminal hydrolase of Drosophila melanogaster in Pichia pastoris
por: Jin, Feng-liang, et al.
Publicado: (2009)

Circulating Ubiquitin Carboxyl Terminal Hydrolase L1 and Neuroglobin Levels in Traumatic Spinal Cord Injuries: Relation to Severity and Outcomes
por: Abuhamdah, Sawsan, et al.
Publicado: (2022)

Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma
por: Yang, Guangshan, et al.
Publicado: (2018)

Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis
por: Nan, Ling, et al.
Publicado: (2016)

Potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 does not predict patient survival in non-small cell lung carcinoma
por: Orr, Katy S, et al.
Publicado: (2011)

Ubiquitin Carboxyl-Terminal Hydrolase L1 of Cardiomyocytes Promotes Macroautophagy and Proteostasis and Protects Against Post-myocardial Infarction Cardiac Remodeling and Heart Failure
por: Wu, Penglong, et al.
Publicado: (2022)

MicroRNA-1288 promotes cell proliferation of human glioblastoma cells by repressing ubiquitin carboxyl-terminal hydrolase CYLD expression
por: Yin, Jun, et al.
Publicado: (2017)

Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF
por: Ge, Jiafeng, et al.
Publicado: (2017)

Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes
por: Bheda, Anjali, et al.
Publicado: (2009)

Ubiquitin C-terminal Hydrolase L1 Regulates Lipid Raft-dependent Endocytosis
por: Kang, Seo-Jun, et al.
Publicado: (2018)

The requirement of ubiquitin C-terminal hydrolase L1 in mouse ovarian development and fertility(†)
por: Woodman, Morgan F, et al.
Publicado: (2022)

Increased expression of ubiquitin C-terminal hydrolase L1 in astrocytomas of ascending grades
por: İzci, Emir Kaan, et al.
Publicado: (2023)

Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease
por: Zetterberg, Madeleine, et al.
Publicado: (2010)

Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa)
por: Wang, Dong-Hui, et al.
Publicado: (2018)

Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease
por: Tran, Hiep H., et al.
Publicado: (2018)

Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region
por: Zhang, Linlin, et al.
Publicado: (2014)

Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1
por: Shimshek, Derya R., et al.
Publicado: (2012)

Positive Reciprocal Regulation of Ubiquitin C-Terminal Hydrolase L1 and β-Catenin/TCF Signaling
por: Bheda, Anjali, et al.
Publicado: (2009)

Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites
por: Ilic, Aleksandar, et al.
Publicado: (2017)

Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1
por: Krabill, Aaron D., et al.
Publicado: (2021)

Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3
por: Hewitt, Chad S., et al.
Publicado: (2022)

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction
por: Bishop, Paul, et al.
Publicado: (2016)

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
por: Bett, John S., et al.
Publicado: (2015)

Significance of Ubiquitin Carboxy-Terminal Hydrolase L1 Elevations in Athletes after Sub-Concussive Head Hits
por: Puvenna, Vikram, et al.
Publicado: (2014)

Ubiquitin C‐terminal hydrolase L1 (UCHL1), a double‐edged sword in mammalian oocyte maturation and spermatogenesis
por: Yang, Donghui, et al.
Publicado: (2022)

Carboxylic ester hydrolases from hyperthermophiles
por: Levisson, Mark, et al.
Publicado: (2009)

Ubiquitin C-Terminal Hydrolase L1 Is Expressed in Mouse Pituitary Gonadotropes In Vivo and Gonadotrope Cell Lines In Vitro
por: Xu, Yang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6g37g5tj58lk2heps4gfgjiiga