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Tumor‐associated macrophages secrete CC‐chemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer

Breast cancer is the most prevalent malignancy among women. Although endocrine therapy is effective, the development of endocrine resistance is a major clinical challenge. The tumor microenvironment (TME) promotes tumor malignancy, and tumor‐associated macrophages (TAM) within the TME play a crucial...

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Detalles Bibliográficos
Autores principales: Li, Dongbo, Ji, Hongfei, Niu, Xingjian, Yin, Lei, Wang, Yiran, Gu, Yucui, Wang, Jinlu, Zhou, Xiaoping, Zhang, Han, Zhang, Qingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942430/
https://www.ncbi.nlm.nih.gov/pubmed/31710162
http://dx.doi.org/10.1111/cas.14230