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Qualitative transcriptional signature for predicting pathological response of colorectal cancer to FOLFOX therapy

FOLFOX (5‐fluorouracil, leucovorin and oxaliplatin) is one of the main chemotherapy regimens for colorectal cancer (CRC), but only half of CRC patients respond to this regimen. Using gene expression profiles of 96 metastatic CRC patients treated with FOLFOX, we first selected gene pairs whose within...

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Detalles Bibliográficos
Autores principales: He, Jun, Cheng, Jun, Guan, Qingzhou, Yan, Haidan, Li, Yawei, Zhao, Wenyuan, Guo, Zheng, Wang, Xianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942442/
https://www.ncbi.nlm.nih.gov/pubmed/31785020
http://dx.doi.org/10.1111/cas.14263