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Kinase activity of ERBB3 contributes to intestinal organoids growth and intestinal tumorigenesis

As a member of the epidermal growth factor receptor (EGFR) family, ERBB3 plays an essential role in development and disease independent of inherently inactive kinase domain. Recently, ERBB3 has been found to bind to ATP and has catalytic activity in vitro. However, the biological function of ERBB3 k...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Thai‐Quynh, Lee, So‐young, Chin, Hyun Jung, Le, Quy Van‐Chanh, Lee, Daekee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942447/
https://www.ncbi.nlm.nih.gov/pubmed/31724799
http://dx.doi.org/10.1111/cas.14235