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Effects of Surface Characteristics of Polymeric Nanocapsules on the Pharmacokinetics and Efficacy of Antimalarial Quinine

INTRODUCTION: The surface charge of nanoparticles, such as nanospheres (NS) and nanocapsules (NC), has been studied with the purpose of improving the in vivo performance of drugs. The aim of this study was to develop, characterize, and evaluate the in vitro antimalarial efficacy of NCP80 and NSP80 (...

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Detalles Bibliográficos
Autores principales: Michels, Luana Roberta, Maciel, Tamara Ramos, Nakama, Kelly Ayumi, Teixeira, Flavia Elizabete Guerra, de Carvalho, Felipe Barbosa, Gundel, André, de Araujo, Bibiana Verlindo, Haas, Sandra Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942527/
https://www.ncbi.nlm.nih.gov/pubmed/32021159
http://dx.doi.org/10.2147/IJN.S227914