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A Chemotherapy-Driven Increase in Mcl-1 Mediates the Effect of miR-375 on Cisplatin Resistance in Osteosarcoma Cells

BACKGROUND: Osteosarcoma (OS) is one of the most difficult cancers to treat due to its resistance to chemotherapy. The essential role played by Mcl-1 in promoting chemoresistance has been observed in a variety of cancers, including OS, while the underlying mechanism remains unclear. METHODS: We inve...

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Detalles Bibliográficos
Autores principales: Liu, An-song, Yu, Hai-yang, Yang, Yan-lin, Xue, Fu-yao, Chen, Xia, Zhang, Yun, Zhou, Zi-yu, Zhang, Bin, Li, Lan, Sun, Chuan-zheng, Huang, Peng, Huang, Ju-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942534/
https://www.ncbi.nlm.nih.gov/pubmed/32021245
http://dx.doi.org/10.2147/OTT.S231125