Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers

Recent innovations in the next-generation sequencing technologies have unveiled that the accumulation of genetic alterations results in the transformation of normal cells into cancer cells. Accurate and timely repair of DNA is, therefore, essential for maintaining genetic stability. Among various DN...

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Detalles Bibliográficos
Autores principales: Eso, Yuji, Shimizu, Takahiro, Takeda, Haruhiko, Takai, Atsushi, Marusawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942585/
https://www.ncbi.nlm.nih.gov/pubmed/31494725
http://dx.doi.org/10.1007/s00535-019-01620-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942585/
https://www.ncbi.nlm.nih.gov/pubmed/31494725
http://dx.doi.org/10.1007/s00535-019-01620-7

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