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Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers
Recent innovations in the next-generation sequencing technologies have unveiled that the accumulation of genetic alterations results in the transformation of normal cells into cancer cells. Accurate and timely repair of DNA is, therefore, essential for maintaining genetic stability. Among various DN...
Autores principales: | Eso, Yuji, Shimizu, Takahiro, Takeda, Haruhiko, Takai, Atsushi, Marusawa, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942585/ https://www.ncbi.nlm.nih.gov/pubmed/31494725 http://dx.doi.org/10.1007/s00535-019-01620-7 |
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