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Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases

Using midbrain cultures, we previously demonstrated that the noble gas xenon is robustly protective for dopamine (DA) neurons exposed to l-trans-pyrrolidine-2,4-dicarboxylate (PDC), an inhibitor of glutamate uptake used to generate sustained, low-level excitotoxic insults. DA cell rescue was observe...

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Detalles Bibliográficos
Autores principales: Le Nogue, Déborah, Lavaur, Jérémie, Milet, Aude, Ramirez-Gil, Juan Fernando, Katz, Ira, Lemaire, Marc, Farjot, Géraldine, Hirsch, Etienne C., Michel, Patrick Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942589/
https://www.ncbi.nlm.nih.gov/pubmed/31807953
http://dx.doi.org/10.1007/s00702-019-02112-x