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IL-6 deficiency attenuates p53 protein accumulation in aged male mouse hippocampus

Our earlier studies demonstrated slower age-related memory decline in IL-6-deficient than in control mice. Therefore, in the present study we evaluated the effect of IL-6 deficiency and aging on expression of p53, connected with accumulation of age-related cellular damages, in hippocampus of 4- and...

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Detalles Bibliográficos
Autores principales: Bialuk, Izabela, Cieślińska, Magdalena, Kowalczuk, Oksana, Bonda, Tomasz A., Nikliński, Jacek, Winnicka, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942598/
https://www.ncbi.nlm.nih.gov/pubmed/31598806
http://dx.doi.org/10.1007/s10522-019-09841-2