TAK-875 Mitigates β-Cell Lipotoxicity-Induced Metaflammation Damage through Inhibiting the TLR4-NF-κB Pathway

Metabolic inflammatory damage, characterized by Toll-like receptor 4 (TLR4) signaling activation, is a major mechanism underlying lipotoxicity-induced β-cell damage. The present study is aimed at determining whether G protein-coupled receptor 4 (GPR40) agonist can improve β-cell lipotoxicity-induced...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xide, Yan, Yuanli, Weng, Zhiyan, Chen, Chao, Lv, Miaoru, Lin, Qingwen, Du, Qiuxia, Shen, Ximei, Yang, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942802/
https://www.ncbi.nlm.nih.gov/pubmed/31934590
http://dx.doi.org/10.1155/2019/5487962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942802/
https://www.ncbi.nlm.nih.gov/pubmed/31934590
http://dx.doi.org/10.1155/2019/5487962

Ejemplares similares