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TAK-875 Mitigates β-Cell Lipotoxicity-Induced Metaflammation Damage through Inhibiting the TLR4-NF-κB Pathway

Metabolic inflammatory damage, characterized by Toll-like receptor 4 (TLR4) signaling activation, is a major mechanism underlying lipotoxicity-induced β-cell damage. The present study is aimed at determining whether G protein-coupled receptor 4 (GPR40) agonist can improve β-cell lipotoxicity-induced...

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Detalles Bibliográficos
Autores principales:	Chen, Xide, Yan, Yuanli, Weng, Zhiyan, Chen, Chao, Lv, Miaoru, Lin, Qingwen, Du, Qiuxia, Shen, Ximei, Yang, Liyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942802/ https://www.ncbi.nlm.nih.gov/pubmed/31934590 http://dx.doi.org/10.1155/2019/5487962

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