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Metformin Protects against Oxidative Stress Injury Induced by Ischemia/Reperfusion via Regulation of the lncRNA-H19/miR-148a-3p/Rock2 Axis

Previous studies have shown that metformin not only is a hypoglycemic agent but also has neuroprotective effects. However, the mechanism of action of metformin in ischemic stroke is unclear. Oxidative stress is an important factor in the pathogenesis of cerebral ischemia-reperfusion injury. It has b...

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Detalles Bibliográficos
Autores principales: Zeng, Jing, Zhu, Long, Liu, Jing, Zhu, Tao, Xie, Zhaohui, Sun, Xiaoou, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942897/
https://www.ncbi.nlm.nih.gov/pubmed/31934270
http://dx.doi.org/10.1155/2019/8768327