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Exploring trophoblast-specific Tead4 enhancers through chromatin conformation capture assays followed by functional screening

Tead4 is critical for blastocyst development and trophoblast differentiation. We assayed long-range chromosomal interactions on the Tead4 promoter in mouse embryonic stem (ES) cells and trophoblast stem (TS) cells. Using luciferase reporter assays with ES and TS cells for 34 candidate enhancer regio...

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Detalles Bibliográficos
Autores principales: Tomikawa, Junko, Takada, Shuji, Okamura, Kohji, Terao, Miho, Ogata-Kawata, Hiroko, Akutsu, Hidenori, Tanaka, Satoshi, Hata, Kenichiro, Nakabayashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943130/
https://www.ncbi.nlm.nih.gov/pubmed/31777916
http://dx.doi.org/10.1093/nar/gkz1034