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Evolution-guided engineering of small-molecule biosensors

Allosteric transcription factors (aTFs) have proven widely applicable for biotechnology and synthetic biology as ligand-specific biosensors enabling real-time monitoring, selection and regulation of cellular metabolism. However, both the biosensor specificity and the correlation between ligand conce...

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Detalles Bibliográficos
Autores principales: Snoek, Tim, Chaberski, Evan K, Ambri, Francesca, Kol, Stefan, Bjørn, Sara P, Pang, Bo, Barajas, Jesus F, Welner, Ditte H, Jensen, Michael K, Keasling, Jay D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943132/
https://www.ncbi.nlm.nih.gov/pubmed/31777933
http://dx.doi.org/10.1093/nar/gkz954