Multiple roles of DNA2 nuclease/helicase in DNA metabolism, genome stability and human diseases

DNA2 nuclease/helicase is a structure-specific nuclease, 5′-to-3′ helicase, and DNA-dependent ATPase. It is involved in multiple DNA metabolic pathways, including Okazaki fragment maturation, replication of ‘difficult-to-replicate’ DNA regions, end resection, stalled replication fork processing, and...

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Detalles Bibliográficos
Autores principales: Zheng, Li, Meng, Yuan, Campbell, Judith L, Shen, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943134/
https://www.ncbi.nlm.nih.gov/pubmed/31754720
http://dx.doi.org/10.1093/nar/gkz1101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943134/
https://www.ncbi.nlm.nih.gov/pubmed/31754720
http://dx.doi.org/10.1093/nar/gkz1101

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