A novel 5′-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes

Modifications at the 5′-end of RNAs play a pivotal role in determining their fate. In eukaryotes, the DXO/Rai1 family of enzymes removes numerous 5′-end RNA modifications, thereby regulating RNA turnover. Mouse DXO catalyzes the elimination of incomplete 5′-end caps (including pyrophosphate) and the...

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Detalles Bibliográficos
Autores principales: Doamekpor, Selom K, Gozdek, Agnieszka, Kwasnik, Aleksandra, Kufel, Joanna, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943137/
https://www.ncbi.nlm.nih.gov/pubmed/31777937
http://dx.doi.org/10.1093/nar/gkz1107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943137/
https://www.ncbi.nlm.nih.gov/pubmed/31777937
http://dx.doi.org/10.1093/nar/gkz1107

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