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Growth hormone receptor promotes osteosarcoma cell growth and metastases

Osteosarcoma (OS) is the primary bone malignancy in children and adolescents, with a high incidence of lung metastasis and poor prognosis. Here, we report that growth hormone receptor (GHR) is overexpressed in OS samples compared with osteofibrous dysplasia. We subsequently demonstrated that GHR kno...

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Detalles Bibliográficos
Autores principales: Cheng, Mo, Huang, Wending, Cai, Weiluo, Fang, Meng, Chen, Yong, Wang, Chunmeng, Yan, Wangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943229/
https://www.ncbi.nlm.nih.gov/pubmed/31725956
http://dx.doi.org/10.1002/2211-5463.12761