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Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures

OBJECTIVE: Despite improvements in imaging, serum CA19-9 and pathological evaluation, differentiating between benign and malignant bile duct strictures remains a diagnostic conundrum. Recent developments in next-generation sequencing (NGS) have opened new opportunities for early detection and manage...

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Detalles Bibliográficos
Autores principales: Singhi, Aatur D, Nikiforova, Marina N, Chennat, Jennifer, Papachristou, Georgios I, Khalid, Asif, Rabinovitz, Mordechai, Das, Rohit, Sarkaria, Savreet, Ayasso, M Samir, Wald, Abigail I, Monaco, Sara E, Nalesnik, Michael, Ohori, N Paul, Geller, David, Tsung, Allan, Zureikat, Amer H, Zeh, Herbert, Marsh, J Wallis, Hogg, Melissa, Lee, Kenneth, Bartlett, David L, Pingpank, James F, Humar, Abhinav, Bahary, Nathan, Dasyam, Anil K, Brand, Randall, Fasanella, Kenneth E, McGrath, Kevin, Slivka, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943248/
https://www.ncbi.nlm.nih.gov/pubmed/30971436
http://dx.doi.org/10.1136/gutjnl-2018-317817