Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15

OBJECTIVE: To investigate molecular changes in multiple sclerosis (MS) normal-appearing cortical gray matter (NAGM). METHODS: We performed a whole-genome gene expression microarray analysis of human brain autopsy tissues from 64 MS NAGM samples and 42 control gray matter samples. We further examined...

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Detalles Bibliográficos
Autores principales: Enz, Lukas Simon, Zeis, Thomas, Schmid, Daniela, Geier, Florian, van der Meer, Franziska, Steiner, Guido, Certa, Ulrich, Binder, Thomas Martin Christian, Stadelmann, Christine, Martin, Roland, Schaeren-Wiemers, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943368/
https://www.ncbi.nlm.nih.gov/pubmed/31882398
http://dx.doi.org/10.1212/NXI.0000000000000656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943368/
https://www.ncbi.nlm.nih.gov/pubmed/31882398
http://dx.doi.org/10.1212/NXI.0000000000000656

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