Novel Homo-Bivalent and Polyvalent Compounds Based on Ligustrazine and Heterocyclic Ring as Anticancer Agents

Bivalent and polyvalent inhibitors can be used as antitumor agents. In this experiment, eight ligustrazine dimers and seven ligustrazine tetramers linked by alkane diamine with different lengths of carbon chain lengths were synthesized. After screening their antiproliferation activities against five...

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Detalles Bibliográficos
Autores principales: Wang, Jiawen, Hong, Ge, Li, Guoliang, Wang, Wenzhi, Liu, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943434/
https://www.ncbi.nlm.nih.gov/pubmed/31835359
http://dx.doi.org/10.3390/molecules24244505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943434/
https://www.ncbi.nlm.nih.gov/pubmed/31835359
http://dx.doi.org/10.3390/molecules24244505

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