Neuroprotective Effect of CR-777, a Glutathione Derivative of Withaferin A, Obtained through the Bioconversion of Withania somnifera (L.) Dunal Extract by the Fungus Beauveria bassiana

The bioconversion of Withania somnifera extract by the fungus Beauveria bassiana leads to cysteine and glutathione derivatives of withaferin A at the C-6 position. The compounds were purified and fully characterized by 1D-NMR, 2D-NMR, and HRMS analysis. The glutathione derivative CR-777 was evaluate...

Descripción completa

Detalles Bibliográficos
Autores principales: Rabhi, Chérif, Arcile, Guillaume, Le Goff, Géraldine, Da Costa Noble, Christian, Ouazzani, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943490/
https://www.ncbi.nlm.nih.gov/pubmed/31888204
http://dx.doi.org/10.3390/molecules24244599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943490/
https://www.ncbi.nlm.nih.gov/pubmed/31888204
http://dx.doi.org/10.3390/molecules24244599

Ejemplares similares