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Neuroprotective Effect of CR-777, a Glutathione Derivative of Withaferin A, Obtained through the Bioconversion of Withania somnifera (L.) Dunal Extract by the Fungus Beauveria bassiana
The bioconversion of Withania somnifera extract by the fungus Beauveria bassiana leads to cysteine and glutathione derivatives of withaferin A at the C-6 position. The compounds were purified and fully characterized by 1D-NMR, 2D-NMR, and HRMS analysis. The glutathione derivative CR-777 was evaluate...
Autores principales: | Rabhi, Chérif, Arcile, Guillaume, Le Goff, Géraldine, Da Costa Noble, Christian, Ouazzani, Jamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943490/ https://www.ncbi.nlm.nih.gov/pubmed/31888204 http://dx.doi.org/10.3390/molecules24244599 |
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