Determination of Chemical Stability of Two Oral Antidiabetics, Metformin and Repaglinide in the Solid State and Solutions Using LC-UV, LC-MS, and FT-IR Methods

Firstly, metformin and repaglinide were degraded under high temperature/humidity, UV/VIS light, in different pH and oxidative conditions. Secondly, a new validated LC-UV method was examined, as to whether it validly determined these drugs in the presence of their degradation products and whether it...

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Detalles Bibliográficos
Autores principales: Gumieniczek, Anna, Berecka-Rycerz, Anna, Mroczek, Tomasz, Wojtanowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943551/
https://www.ncbi.nlm.nih.gov/pubmed/31817112
http://dx.doi.org/10.3390/molecules24244430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943551/
https://www.ncbi.nlm.nih.gov/pubmed/31817112
http://dx.doi.org/10.3390/molecules24244430

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