N-acetylcysteine Decreases Fibrosis and Increases Force-Generating Capacity of mdx Diaphragm

Respiratory muscle weakness occurs due to dystrophin deficiency in Duchenne muscular dystrophy (DMD). The mdx mouse model of DMD shows evidence of impaired respiratory muscle performance with attendant inflammation and oxidative stress. We examined the effects of N-acetylcysteine (NAC) supplementati...

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Detalles Bibliográficos
Autores principales: Burns, David P., Drummond, Sarah E., Bolger, Dearbhla, Coiscaud, Amélie, Murphy, Kevin H., Edge, Deirdre, O’Halloran, Ken D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943616/
https://www.ncbi.nlm.nih.gov/pubmed/31771272
http://dx.doi.org/10.3390/antiox8120581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943616/
https://www.ncbi.nlm.nih.gov/pubmed/31771272
http://dx.doi.org/10.3390/antiox8120581

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