Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liability. The growing awareness that multifunctional lig...

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Detalles Bibliográficos
Autores principales: Wtorek, Karol, Adamska-Bartłomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Ferrari, Federica, Ruzza, Chiara, Kluczyk, Alicja, Piasecka-Zelga, Joanna, Calo’, Girolamo, Janecka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943619/
https://www.ncbi.nlm.nih.gov/pubmed/31817441
http://dx.doi.org/10.3390/molecules24244460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943619/
https://www.ncbi.nlm.nih.gov/pubmed/31817441
http://dx.doi.org/10.3390/molecules24244460

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