Identification of High-Affinity Inhibitors of Cyclin-Dependent Kinase 2 Towards Anticancer Therapy

Cyclin-dependent kinase 2 (CDK2) is an essential protein kinase involved in the cell cycle regulation. The abnormal activity of CDK2 is associated with cancer progression and metastasis. Here, we have performed structure-based virtual screening of the PubChem database to identify potent CDK2 inhibit...

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Detalles Bibliográficos
Autores principales: Mohammad, Taj, Batra, Sagar, Dahiya, Rashmi, Baig, Mohammad Hassan, Rather, Irfan Ahmad, Dong, Jae-June, Hassan, Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943647/
https://www.ncbi.nlm.nih.gov/pubmed/31847444
http://dx.doi.org/10.3390/molecules24244589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943647/
https://www.ncbi.nlm.nih.gov/pubmed/31847444
http://dx.doi.org/10.3390/molecules24244589

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