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Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy

Obesity increases the risk of developing diabetes and subsequently, diabetic cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H(2)S) and increased inflammatory cell death via pyroptosis contribute to adverse cardiac remodeling and DMCM. Although exercise training (EX) ha...

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Detalles Bibliográficos
Autores principales: Kar, Sumit, Shahshahan, Hamid R., Hackfort, Bryan T., Yadav, Santosh K., Yadav, Roopali, Kambis, Tyler N., Lefer, David J., Mishra, Paras K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943713/
https://www.ncbi.nlm.nih.gov/pubmed/31835893
http://dx.doi.org/10.3390/antiox8120638