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Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy
Obesity increases the risk of developing diabetes and subsequently, diabetic cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H(2)S) and increased inflammatory cell death via pyroptosis contribute to adverse cardiac remodeling and DMCM. Although exercise training (EX) ha...
Autores principales: | Kar, Sumit, Shahshahan, Hamid R., Hackfort, Bryan T., Yadav, Santosh K., Yadav, Roopali, Kambis, Tyler N., Lefer, David J., Mishra, Paras K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943713/ https://www.ncbi.nlm.nih.gov/pubmed/31835893 http://dx.doi.org/10.3390/antiox8120638 |
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