Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides

There is interest in peptide drug design, especially for targeting intracellular protein–protein interactions. Therefore, the experimental validation of a computational platform for enabling peptide drug design is of interest. Here, we describe our peptide drug design platform (CMDInventus) and demo...

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Detalles Bibliográficos
Autores principales: Diller, David J., Swanson, Jon, Bayden, Alexander S., Brown, Chris J., Thean, Dawn, Lane, David P., Partridge, Anthony W., Sawyer, Tomi K., Audie, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943714/
https://www.ncbi.nlm.nih.gov/pubmed/31847417
http://dx.doi.org/10.3390/molecules24244586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943714/
https://www.ncbi.nlm.nih.gov/pubmed/31847417
http://dx.doi.org/10.3390/molecules24244586

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