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Chronic Oxidative Stress Promotes Molecular Changes Associated with Epithelial Mesenchymal Transition, NRF2, and Breast Cancer Stem Cell Phenotype

Oxidative stress plays a role in carcinogenesis, but it also contributes to the modulation of tumor cells and microenvironment caused by chemotherapeutics. One of the consequences of oxidative stress is lipid peroxidation, which can, through reactive aldehydes such as 4-hydroxy-2-nonenal (HNE), affe...

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Detalles Bibliográficos
Autores principales: Čipak Gašparović, Ana, Milković, Lidija, Dandachi, Nadia, Stanzer, Stefanie, Pezdirc, Iskra, Vrančić, Josip, Šitić, Sanda, Suppan, Christoph, Balic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943739/
https://www.ncbi.nlm.nih.gov/pubmed/31835715
http://dx.doi.org/10.3390/antiox8120633