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Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

Previous optimisation studies of peptide/peptoid hybrids typically comprise comparison of structurally related analogues displaying different oligomer length and diverse side chains. The present work concerns a systematically constructed series of 16 closely related 12-mer oligomers with an alternat...

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Detalles Bibliográficos
Autores principales: Frederiksen, Nicki, Hansen, Paul R., Björkling, Fredrik, Franzyk, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943742/
https://www.ncbi.nlm.nih.gov/pubmed/31817108
http://dx.doi.org/10.3390/molecules24244429