Continuous Flow Photochemical and Thermal Multi-Step Synthesis of Bioactive 3-Arylmethylene-2,3-Dihydro-1H-Isoindolin-1-Ones

An effective multi-step continuous flow approach towards N-diaminoalkylated 3-arylmethylene-2,3-dihydro-1H-isoindolin-1-ones, including the local anesthetic compound AL-12, has been realized. Compared to the traditional decoupled batch processes, the combined photochemical–thermal–thermal flow setup...

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Detalles Bibliográficos
Autores principales: Mumtaz, Saira, Robertson, Mark J., Oelgemöller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943768/
https://www.ncbi.nlm.nih.gov/pubmed/31835663
http://dx.doi.org/10.3390/molecules24244527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943768/
https://www.ncbi.nlm.nih.gov/pubmed/31835663
http://dx.doi.org/10.3390/molecules24244527

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