Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model

BACKGROUND: The FDA approved drug granulocyte-colony stimulating factor (G-CSF) displays anti-apoptotic and immunomodulatory properties with neurogenesis and angiogenic functions. It is known to demonstrate neuroprotective mechanisms against ischemic global stroke. Autophagy is a method for the degr...

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Detalles Bibliográficos
Autores principales: Modi, Jigar, Menzie-Suderam, Janet, Xu, Hongyuan, Trujillo, Paola, Medley, Kristen, Marshall, Michael L., Tao, Rui, Prentice, Howard, Wu, Jang-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943893/
https://www.ncbi.nlm.nih.gov/pubmed/31907023
http://dx.doi.org/10.1186/s12929-019-0597-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943893/
https://www.ncbi.nlm.nih.gov/pubmed/31907023
http://dx.doi.org/10.1186/s12929-019-0597-7

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